KORPUS NIMA VA U NIMA MAQSADDA KERAK?

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Evidence for a NIMA-like mitotic pathway in vertebrate cells

NIMA is essential for entry into mitosis in Aspergillus nidulans. To examine whether there is a NIMA-like pathway in other eukaryotic cell cycles, we expressed NIMA and its dominant negative mutants in two different eukaryotic systems. In Xenopus oocytes, NIMA induced germinal vesicle breakdown without activating Mos, CDC2, or MAP kinase. In HeLa cells, NIMA induced premature mitotic events wit...

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Cell Cycle: The NIMA kinase joins forces with Cdc2

The NIMA and Cdc2 protein kinases cooperate to regulate mitosis in Aspergillus nidulans. NIMA-related pathways have now begun to emerge in higher eukaryotes.

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The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons.

NIMA-related kinases (Neks) belong to a large family of Ser/Thr kinases that have critical roles in coordinating microtubule dynamics during ciliogenesis and mitotic progression. The Nek kinases are also expressed in neurons, whose axonal projections are, similarly to cilia, microtubule-abundant structures that extend from the cell body. We therefore investigated whether Nek kinases have additi...

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ژورنال

عنوان ژورنال: COMPUTER LINGUISTICS: PROBLEMS, SOLUTIONS, PROSPECT

سال: 2021

ISSN: 2181-922X

DOI: 10.52773/cl:psp/vol_1_issue_1/a4